Skip to content
Bramble

Health

Study: colorectal cancer in teens is rare but often advanced and aggressive at diagnosis

A new, not yet peer-reviewed US study of 84 patients aged 21 and under found most colorectal cancers were diagnosed at stage 3 or 4, and 45% of patients died. Researchers urge doctors to take symptoms seriously and are still investigating the causes.

3 outlets · 1L · 0C · 2R First reported Account updated
Image: NBC News
Image: Daily Mail
Image: New York Post

1 / 3

The story, neutrally told

MixedA new study of 84 US patients aged 21 or younger who were diagnosed with colorectal cancer found that the disease is usually advanced and aggressive by the time it is found. LeftAccording to NBC News, the team led by Dr. Danielle Cameron of Mass General Brigham Cancer Institute covered diagnoses from 2012 through 2023, and the findings will be presented at the American Academy of Pediatrics' national conference in San Diego; they have not yet been published in a peer-reviewed journal. MixedAbout 80% of patients were diagnosed at stage 3 or 4; the New York Post reports that more than half were at stage 3 (local spread) and 29% at stage 4 (distant spread).

MixedThe cancer returned in about 37% of patients, and 45% died; the outlets give the median age as 16 (NBC) and 16.5 (New York Post). MixedDiagnosis is hard because symptoms are vague and overlap with common conditions, and young people are decades from routine colonoscopy screening. LeftIn the study, about 74% reported back or abdominal pain, about 45% changes in bowel habits, a similar share unexplained weight loss, and about 32% rectal bleeding.

MixedResearchers and outside experts urge clinicians to take symptoms seriously; Dr. Christopher Lieu of the University of Colorado said doctors should consider colorectal cancer if common causes are ruled out and symptoms do not improve. MixedCases in people under 21 remain very rare, which NBC puts at fewer than 100 a year in the US, but both outlets say rates are rising; the New York Post cites fivefold growth among ages 10 to 14 over two decades. MixedThe cause is unknown: NBC quotes experts pointing to childhood environmental exposures, ultraprocessed food and possible genetic predisposition (only about 20% had a family history), while the Post lists obesity, a Western diet, microplastics, pesticides, antibiotics and infections.

LeftNBC also profiles Jo Henderson, diagnosed at 17 after months of symptoms, whose cancer had spread to her ovaries; after surgery and five months of chemotherapy, an August colonoscopy showed no cancer.

Every sentence links to the reporting it rests on. The pill in front of each says where its sources sit: Left, Centre or Right when one side supplies at least half of them, Mixed when they are evenly split.

Left1 outlet

Framing
A human-centred health feature led by a patient's story, stressing rarity alongside the study's findings and expert caution.
Emphasis
Rarity of cases, diagnostic difficulty, expert quotes, uncertain causes (ultraprocessed food, genetics, exposures) and the peer-review status.
Leaves out or plays down
Does not give population-level growth rates by age band as the Post does.
Charged language
“the million-dollar question”
For example
“Cameron stressed that cases in adolescents and very young adults are “still very, very rare.”” — NBC News

Centre0 outlets

No centre outlet in our sources has covered this story yet.

Right2 outlets

Framing
A service-style piece stressing rising rates and a symptom checklist for readers.
Emphasis
Steep growth figures, deaths and recurrence, symptoms, survival odds with early detection, and lifestyle and environmental suspects.
Leaves out or plays down
Does not say the study is unpublished or note how rare the cases are in absolute terms; quotes no named outside experts.
Charged language
“exploded”
For example
“Over the past two decades, colorectal cancers have exploded fivefold among children ages 10 to 14” — New York Post