Lancet commission lists 17 catastrophic health threats, with AI misuse and nuclear war top
A new Lancet commission of 35 experts has ranked 17 major threats to human health to 2100. It says malicious use of AI and nuclear conflict carry extinction risk, and that a realistic route to act exists on each.
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The story, neutrally told
Left · 2The Lancet Commission on 21st Century Global Threats to Health has published a risk assessment identifying 17 major threats to human health over the next 75 years. The GuardianLC “They top a list of 17 major threats to human health over the next 75 years” Read at The Guardian ↗ MetroLC “Their new report also listed the 17 major dangers to human health over the next 75 years” Read at Metro ↗ Left · 1Two of them, malicious use of AI (including AI-created bioweapons) and nuclear conflict leading to nuclear famine, are said to carry a risk of human extinction within 75 years, although the report says their likelihood remains low. The GuardianLC ““Malicious use of AI, including bioweapons, and nuclear conflict with nuclear famine carry risks of extinction in the next 75 years,” the report said” Read at The Guardian ↗ Left · 2The commission modelled the years of good health lost to sickness, disability or early death for each threat, a measure called disability-adjusted life years (Dalys); threats that could cause more than 1bn cumulative Dalys were deemed "major catastrophic threats". The GuardianLC “a measure known as disability-adjusted life years (Dalys)” Read at The Guardian ↗ MetroLC “The other catastrophic threats could cause more than 1 billion DALYs.” Read at Metro ↗
Left · 2The other 15 threats are air pollution, antimicrobial resistance, childhood malnutrition, climate breakdown, conventional conflict, declining overseas health aid, high alcohol use, high blood pressure, income inequality, low educational attainment, naturally occurring pandemics, obesity, poor mental health, smoking and unhealthy ageing. The GuardianLC “air pollution, antimicrobial resistance, childhood malnutrition and climate breakdown, as well as conventional conflict” Read at The Guardian ↗ MetroLC “Extinction-potential threats:” Read at Metro ↗ Left · 1Metro reports worst-case figures of 9.35bn Dalys for nuclear war and 10.4bn for malicious AI, says nuclear conflict could kill 133 million people by 2100, and puts obesity at 23.1bn Dalys. MetroLC “nuclear war could wipe out 9.35 billion DALYs”“Scientists from The Lancet said nuclear conflict could kill 133 million people by 2100.”“contributing to 23.1 billion DALYs by 2100” Read at Metro ↗ Left · 2Limiting global heating to about 1.8C rather than 4.4C could prevent 1.89bn lost years of healthy life, according to the report. The GuardianLC “could prevent 1.89bn years of healthy life being lost” Read at The Guardian ↗ MetroLC “1.89 billion DALYs could be saved” Read at Metro ↗
Left · 1The Guardian reports that a collapse or steep reduction in international health aid could cause up to 1.5bn Dalys before 2100, nearly 70% of them in sub-Saharan Africa, following aid cuts by donors including the US and UK. The GuardianLC “could cause up to 1.5bn Dalys before 2100, the commission found, nearly 70% of which would be in sub-Saharan Africa” Read at The Guardian ↗ Left · 1Metro adds that faster progress on education for women and children in sub-Saharan Africa could stop the loss of 16.1bn healthy years. MetroLC “could stop the loss of 16.1 billion healthy years” Read at Metro ↗ Left · 2Co-chair Prof Christopher Murray of the Institute for Health Metrics and Evaluation, University of Washington, said leaders' decisions today will shape the next generation's health, that the threats are interconnected and must be addressed together, and that delay shifts and raises costs. The GuardianLC ““Decisions made by leaders today will shape the health and wellbeing of the next generation,” said Prof Christopher Murray” Read at The Guardian ↗ MetroLC “all 17 threats are interconnected, which is why they must be addressed together, not in isolation.” Read at Metro ↗
Left · 1Commission member Ibrahim Abubakar of UCL said the aim was not to scare people but to show policymakers the magnitude of difference that action can make; to be listed, a threat also had to have potential solutions. The GuardianLC “We are not starting from a point of view of ‘oh look, we want to scare you”“To be included on the list, threats not only had to potentially cause a high number of lost healthy years, but also to have potential solutions.” Read at The Guardian ↗ Left · 2The 35-member commission calls for readiness to manage the threats, support for scientific innovation and better tracking of emerging hazards; its findings were to be presented at the World Health Summit in Berlin, and the assessment will be updated annually. The GuardianLC “The commission was made up of 35 experts, and its findings will be shared on Sunday at the World Health Summit in Berlin, Germany.” Read at The Guardian ↗ MetroLC “building readiness to manage these threats, back scientific breakthroughs and innovation, and better tracking of potential threats” Read at Metro ↗
Every sentence links to the reporting it rests on. The pill in front of each says where its sources sit: Left, Centre or Right when one side supplies at least half of them, Mixed when they are evenly split. The number is how many outlets it cites.
Left2 outlets
- Framing
- Both outlets lead on the extinction risk from nuclear war and malicious AI, then list the other threats and the call for early action.
- Emphasis
- The Guardian stresses the commission's method, aid cuts and sub-Saharan Africa; Metro stresses large DALY figures, obesity and a full list.
- Leaves out or plays down
- Metro does not say the extinction likelihood is low or mention aid cuts by donor countries; the Guardian omits the 133 million death estimate and the per-threat DALY figures for nuclear war, AI and obesity.
- Charged language
- “end of humanity”“wipe us out”“apocalypse on humanity”
- For example
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“Nuclear war and malicious use of AI threaten end of humanity by 2100, says Lancet assessment” — The Guardian
“Greatest threats to human survival revealed as two could wipe us out by next century” — Metro
Centre0 outlets
No centre outlet in our sources has covered this story yet.
Right0 outlets
No right outlet in our sources has covered this story yet.
What every side reports
- The commission identified 17 major threats to health over the next 75 years.
- Malicious use of AI and nuclear conflict are the two threats with extinction potential.
- Limiting warming to 1.8C rather than 4.4C could save 1.89bn Dalys.
- Co-chair Christopher Murray said the threats are interconnected and must be addressed together.
The Lancet organisation
Through its commission and an accompanying editorial, The Lancet presents the threats as severe but addressable, warning of an "apocalypse on humanity" if the worst risks are realised.
“The scale of harm, should they be realised, would inflict an apocalypse on humanity.” — The Guardian
“there was “a realistic route to act” on each” — The Guardian
Artificial intelligence topic
Malicious use of AI, including AI-created biological weapons, is named as one of two threats with extinction potential.
“Malicious use of AI, including bioweapons, and nuclear conflict with nuclear famine carry risks of extinction in the next 75 years” — The Guardian
Left2 articles
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Nuclear war and malicious use of AI threaten end of humanity by 2100, says Lancet assessment
Neutral Detailed report that leads on extinction risk but includes the commission's caveats on low likelihood and its emphasis on action.

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MetroLC ·
Greatest threats to human survival revealed as two could wipe us out by next century
Alarmist Headline-led listicle emphasising extinction and large DALY figures, with the commission's calls to act placed lower.

Centre0 articles
No coverage yet.
Right0 articles
No coverage yet.
- 11 Oct 00:01 First The GuardianLC Nuclear war and malicious use of AI threaten end of humanity by 2100, says Lancet assessment
- 11 Oct 11:20 +11h 19m MetroLC Greatest threats to human survival revealed as two could wipe us out by next century
Times are when each article was published, or when we first saw it if the outlet gave no time.