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Choline supplement in pregnancy linked to 8-point IQ-test gain in 4-year-olds

A University of Colorado randomized trial found children of mothers given high-dose phosphatidylcholine, a form of choline, in pregnancy scored about 8 points higher on an IQ-style test at age 4 and showed fewer social withdrawal behaviors. CBS News discussed the research on air.

2 outlets · 1L · 0C · 1R First reported Account updated
Image: New York Post
Image: CBS News

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The story, neutrally told

Right · 1A clinical trial from the University of Colorado reported that children of mothers who took phosphatidylcholine, a form of choline, during pregnancy had better outcomes in language, social behavior and cognitive testing. Right · 1Four-year-olds whose mothers took high doses scored about 8 points higher on an IQ-style test than those whose mothers took a placebo, according to the New York Post's report. Right · 1The trial is described as the largest randomized clinical trial of prenatal choline supplementation to date. It involved more than 200 pregnant women taking 9,000 milligrams of phosphatidylcholine, with the rest taking a placebo, from 16 weeks of pregnancy until delivery. Neither the women nor the researchers knew who received which until the end.

Right · 1Children's behavior was assessed from 18 months to 4 years, and cognitive performance was measured at ages 3 and 4. Right · 1By age four, 4% of children in the supplement group showed multiple or lasting social withdrawal problems, compared with 24% in the placebo group. Fewer children in the supplement group also had behavioral and language profiles often associated with autism. Right · 1There were limits: attention problems did not improve notably, and around one-third of participants dropped out before the final assessments.

Right · 1Senior author Robert Freedman said in a press release that the study adds evidence that choline in pregnancy can have lasting effects on brain development. Freedman said many mothers do not get enough choline from diet, and the study authors describe the findings as showing "safe, effective support of fetal brain development". Right · 1The researchers believe the dose used was somewhat higher than needed and recommend 7,200 mg of phosphatidylcholine, or 900 mg of choline itself. Left · 1On 28 October, CBS News featured Dr. Céline Gounder on "CBS Mornings" to discuss new research suggesting a certain prenatal supplement could affect a child's IQ.

Every sentence links to the reporting it rests on. The pill in front of each says where its sources sit: Left, Centre or Right when one side supplies at least half of them, Mixed when they are evenly split. The number is how many outlets it cites.

Left1 outlet

Framing
CBS News presents the research as a explainer-style television segment, with Dr. Céline Gounder discussing whether a prenatal vitamin can affect a child's IQ.
Emphasis
The question of IQ impact for parents, framed through a medical expert.
Leaves out or plays down
The available CBS coverage gives no trial figures, dosage or limitations.
For example
“Can a prenatal vitamin impact your child's IQ?” — CBS News

Centre0 outlets

No centre outlet in our sources has covered this story yet.

Right1 outlet

Framing
The New York Post leads with the IQ and social-skills benefit, calling the supplement "surprising", and reports the trial's results in detail along with caveats.
Emphasis
The 8-point IQ gain, the drop in social withdrawal (4% vs 24%), and the researchers' quotes and dosage advice.
Leaves out or plays down
Does not give an independent expert view; relies on the study authors and a press release.
Charged language
“surprising supplement”“baby boost”
For example
“A surprising supplement may give babies an IQ boost and social skills: study” — New York Post
“This supplement is certainly a baby boost.” — New York Post

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